ParkinsonCanadaV1, France, Analysis, bibRecord, 000147

Effect of co-morbidities on fracture risk: Findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW)

Identifieur interne : 000147 ( France/Analysis ); précédent : 000146; suivant : 000148

Effect of co-morbidities on fracture risk: Findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW)

Auteurs : Elaine M. Dennison [Royaume-Uni, Nouvelle-Zélande] ; Juliet E. Compston [Royaume-Uni] ; Julie Flahive [États-Unis] ; Ethel S. Siris [États-Unis] ; Stephen H. Gehlbach [États-Unis] ; Jonathan D. Adachi [Canada] ; Steven Boonen [Belgique] ; Roland Chapurlat [France] ; Adolfo Diez-Perez [Espagne] ; Frederick A. Jr Anderson [États-Unis] ; Frederick H. Hooven [États-Unis] ; Andrea Z. Lacroix [États-Unis] ; Robert Lindsay [États-Unis] ; J. Coen Netelenbos [Pays-Bas] ; Johannes Pfeilschifter [Allemagne] ; Maurizio Rossini [Italie] ; Christian Roux [France] ; Kenneth G. Saag [États-Unis] ; Philip Sambrook [Australie] ; Stuart Silverman [États-Unis] ; Nelson B. Watts [États-Unis] ; Susan L. Greenspan [États-Unis] ; Melissa Premaor ; Cyrus Cooper [Royaume-Uni]

Source :

Bone : (New York, NY) [ 8756-3282 ] ; 2012.

RBID : Pascal:13-0082487

Descripteurs français

Pascal (Inist)
- Epidémiologie, Morbidité, Fracture, Facteur risque, Ostéoporose, Femme, Maladie de Parkinson, Sclérose en plaques, Morphologie, Pronostic.
Wicri :
- topic : Femme.

English descriptors

KwdEn :
- Epidemiology, Fracture, Morbidity, Morphology, Multiple sclerosis, Osteoporosis, Parkinson disease, Prognosis, Risk factor, Woman.

Abstract

Introduction: Greater awareness of the relationship between co-morbidities and fracture risk may improve fracture-prediction algorithms such as FRAX. Materials and methods: We used a large, multinational cohort study (GLOW) to investigate the effect of co-morbidities on fracture risk. Women completed a baseline questionnaire detailing past medical history, including co-morbidity history and fracture. They were re-contacted annually to determine incident clinical fractures. A co-morbidity index, defined as number of baseline co-morbidities, was derived. The effect of adding the co-morbidity index to FRAX risk factors on fracture prevention was examined using chi-squared tests, the May-Hosmer test, c index and comparison of predicted versus observed fracture rates. Results: Of 52,960 women with follow-up data, enrolled between October 2006 and February 2008, 3224 (6.1%) sustained an incident fracture over 2 years. All recorded co-morbidities were significantly associated with fracture, except for high cholesterol, hypertension, celiac disease, and cancer. The strongest association was seen with Parkinson's disease (age-adjusted hazard ratio [HR]: 2.2; 95% Cl: 1.6-3.1; P<0.001). Co-morbidities that contributed most to fracture prediction in a Cox regression model with FRAX risk factors as additional predictors were: Parkinson's disease, multiple sclerosis, chronic obstructive pulmonary disease, osteoarthritis, and heart disease. Conclusion: Co-morbidities, as captured in a co-morbidity index, contributed significantly to fracture risk in this study population. Parkinson's disease carried a particularly high risk of fracture; and increasing comorbidity index was associated with increasing fracture risk. Addition of co-morbidity index to FRAX risk factors improved fracture prediction.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886309

Affiliations:

Links to Exploration step

Pascal:13-0082487

Le document en format XML

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<author><name sortKey="Premaor, Melissa" sort="Premaor, Melissa" uniqKey="Premaor M" first="Melissa" last="Premaor">Melissa Premaor</name>
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<author><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital</s1>
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<author><name sortKey="Adachi, Jonathan D" sort="Adachi, Jonathan D" uniqKey="Adachi J" first="Jonathan D." last="Adachi">Jonathan D. Adachi</name>
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<s2>Hamilton, Ontario</s2>
<s3>CAN</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
<region type="state">Ontario</region>
</placeName>
<orgName type="university">Université McMaster</orgName>
</affiliation>
</author>
<author><name sortKey="Boonen, Steven" sort="Boonen, Steven" uniqKey="Boonen S" first="Steven" last="Boonen">Steven Boonen</name>
<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Leuven University Center for Metabolic Bone Diseases, Division of Geriatric Medicine, Ka<sub>th</sub>
olieke Universitei<sub>t</sub>
 Leuven</s1>
<s2>Leuven</s2>
<s3>BEL</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Belgique</country>
<wicri:noRegion>Leuven</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chapurlat, Roland" sort="Chapurlat, Roland" uniqKey="Chapurlat R" first="Roland" last="Chapurlat">Roland Chapurlat</name>
<affiliation wicri:level="3"><inist:fA14 i1="08"><s1>INSERM U831, Universite de Lyon, Division of Rheumatology, Hôpital E. Herriot</s1>
<s2>Lyon</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Diez Perez, Adolfo" sort="Diez Perez, Adolfo" uniqKey="Diez Perez A" first="Adolfo" last="Diez-Perez">Adolfo Diez-Perez</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Hospital del Mar-IMIM-Autonomous University of Barcelona</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Anderson, Frederick A Jr" sort="Anderson, Frederick A Jr" uniqKey="Anderson F" first="Frederick A. Jr" last="Anderson">Frederick A. Jr Anderson</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Center for Outcomes Research, UMASS Medical School</s1>
<s2>Worcester, MA</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Worcester, MA</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hooven, Frederick H" sort="Hooven, Frederick H" uniqKey="Hooven F" first="Frederick H." last="Hooven">Frederick H. Hooven</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Center for Outcomes Research, UMASS Medical School</s1>
<s2>Worcester, MA</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Worcester, MA</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lacroix, Andrea Z" sort="Lacroix, Andrea Z" uniqKey="Lacroix A" first="Andrea Z." last="Lacroix">Andrea Z. Lacroix</name>
<affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Fred Hutchinson Cancer Research Center</s1>
<s2>Seattle, WA</s2>
<s3>USA</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Fred Hutchinson Cancer Research Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lindsay, Robert" sort="Lindsay, Robert" uniqKey="Lindsay R" first="Robert" last="Lindsay">Robert Lindsay</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Regional Bone Center, Helen Hayes Hospital</s1>
<s2>West Haverstraw, NY</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>West Haverstraw, NY</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Coen Netelenbos, J" sort="Coen Netelenbos, J" uniqKey="Coen Netelenbos J" first="J." last="Coen Netelenbos">J. Coen Netelenbos</name>
<affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Endocrinology, VU University Medical Center</s1>
<s2>Amsterdam</s2>
<s3>NLD</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pfeilschifter, Johannes" sort="Pfeilschifter, Johannes" uniqKey="Pfeilschifter J" first="Johannes" last="Pfeilschifter">Johannes Pfeilschifter</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Alfried Krupp Krankenhaus, Department of Internal Medicine III</s1>
<s2>Essen</s2>
<s3>DEU</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Essen</wicri:noRegion>
<wicri:noRegion>Department of Internal Medicine III</wicri:noRegion>
<wicri:noRegion>Essen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rossini, Maurizio" sort="Rossini, Maurizio" uniqKey="Rossini M" first="Maurizio" last="Rossini">Maurizio Rossini</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Rheumatology, University of Verona</s1>
<s2>Verona</s2>
<s3>ITA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Verona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Roux, Christian" sort="Roux, Christian" uniqKey="Roux C" first="Christian" last="Roux">Christian Roux</name>
<affiliation wicri:level="3"><inist:fA14 i1="15"><s1>Paris Descartes University, Cochin Hospital</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Saag, Kenneth G" sort="Saag, Kenneth G" uniqKey="Saag K" first="Kenneth G." last="Saag">Kenneth G. Saag</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>University of Alabama-Birmingham</s1>
<s2>Birmingham, AL</s2>
<s3>USA</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>University of Alabama-Birmingham</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sambrook, Philip" sort="Sambrook, Philip" uniqKey="Sambrook P" first="Philip" last="Sambrook">Philip Sambrook</name>
<affiliation wicri:level="3"><inist:fA14 i1="17"><s1>University of Sydney-Royal North Shore Hospital, St. Leonards, Sydney</s1>
<s2>New South Wales</s2>
<s3>AUS</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Sydney</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Silverman, Stuart" sort="Silverman, Stuart" uniqKey="Silverman S" first="Stuart" last="Silverman">Stuart Silverman</name>
<affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Department of Rheumatology, Cedars-Sinai/UCLA</s1>
<s2>Los Angeles, CA</s2>
<s3>USA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Los Angeles, CA</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Watts, Nelson B" sort="Watts, Nelson B" uniqKey="Watts N" first="Nelson B." last="Watts">Nelson B. Watts</name>
<affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Bone Health and Osteoporosis Center, University of Cincinnati</s1>
<s2>Cincinnati, OH</s2>
<s3>USA</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Cincinnati, OH</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Greenspan, Susan L" sort="Greenspan, Susan L" uniqKey="Greenspan S" first="Susan L." last="Greenspan">Susan L. Greenspan</name>
<affiliation wicri:level="4"><inist:fA14 i1="20"><s1>University of Pittsburgh</s1>
<s2>Pittsburgh, PA</s2>
<s3>USA</s3>
<sZ>22 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><settlement type="city">Pittsburgh</settlement>
<region type="state">Pennsylvanie</region>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Premaor, Melissa" sort="Premaor, Melissa" uniqKey="Premaor M" first="Melissa" last="Premaor">Melissa Premaor</name>
</author>
<author><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital</s1>
<s2>Southampton</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>24 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Southampton</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Bone : (New York, NY)</title>
<title level="j" type="abbreviated">Bone : (NY NY)</title>
<idno type="ISSN">8756-3282</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Bone : (New York, NY)</title>
<title level="j" type="abbreviated">Bone : (NY NY)</title>
<idno type="ISSN">8756-3282</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Epidemiology</term>
<term>Fracture</term>
<term>Morbidity</term>
<term>Morphology</term>
<term>Multiple sclerosis</term>
<term>Osteoporosis</term>
<term>Parkinson disease</term>
<term>Prognosis</term>
<term>Risk factor</term>
<term>Woman</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Epidémiologie</term>
<term>Morbidité</term>
<term>Fracture</term>
<term>Facteur risque</term>
<term>Ostéoporose</term>
<term>Femme</term>
<term>Maladie de Parkinson</term>
<term>Sclérose en plaques</term>
<term>Morphologie</term>
<term>Pronostic</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Femme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Introduction: Greater awareness of the relationship between co-morbidities and fracture risk may improve fracture-prediction algorithms such as FRAX. Materials and methods: We used a large, multinational cohort study (GLOW) to investigate the effect of co-morbidities on fracture risk. Women completed a baseline questionnaire detailing past medical history, including co-morbidity history and fracture. They were re-contacted annually to determine incident clinical fractures. A co-morbidity index, defined as number of baseline co-morbidities, was derived. The effect of adding the co-morbidity index to FRAX risk factors on fracture prevention was examined using chi-squared tests, the May-Hosmer test, c index and comparison of predicted versus observed fracture rates. Results: Of 52,960 women with follow-up data, enrolled between October 2006 and February 2008, 3224 (6.1%) sustained an incident fracture over 2 years. All recorded co-morbidities were significantly associated with fracture, except for high cholesterol, hypertension, celiac disease, and cancer. The strongest association was seen with Parkinson's disease (age-adjusted hazard ratio [HR]: 2.2; 95% Cl: 1.6-3.1; P<0.001). Co-morbidities that contributed most to fracture prediction in a Cox regression model with FRAX risk factors as additional predictors were: Parkinson's disease, multiple sclerosis, chronic obstructive pulmonary disease, osteoarthritis, and heart disease. Conclusion: Co-morbidities, as captured in a co-morbidity index, contributed significantly to fracture risk in this study population. Parkinson's disease carried a particularly high risk of fracture; and increasing comorbidity index was associated with increasing fracture risk. Addition of co-morbidity index to FRAX risk factors improved fracture prediction.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Belgique</li>
<li>Canada</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Nouvelle-Zélande</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Angleterre de l'Est</li>
<li>Auvergne-Rhône-Alpes</li>
<li>Catalogne</li>
<li>Hollande-Septentrionale</li>
<li>Ontario</li>
<li>Pennsylvanie</li>
<li>Rhône-Alpes</li>
<li>Île-de-France</li>
</region>
<settlement><li>Amsterdam</li>
<li>Barcelone</li>
<li>Cambridge</li>
<li>Hamilton (Ontario)</li>
<li>Lyon</li>
<li>Paris</li>
<li>Pittsburgh</li>
<li>Sydney</li>
</settlement>
<orgName><li>Université McMaster</li>
<li>Université de Cambridge</li>
<li>Université de Pittsburgh</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Premaor, Melissa" sort="Premaor, Melissa" uniqKey="Premaor M" first="Melissa" last="Premaor">Melissa Premaor</name>
</noCountry>
<country name="Royaume-Uni"><noRegion><name sortKey="Dennison, Elaine M" sort="Dennison, Elaine M" uniqKey="Dennison E" first="Elaine M." last="Dennison">Elaine M. Dennison</name>
</noRegion>
<name sortKey="Compston, Juliet E" sort="Compston, Juliet E" uniqKey="Compston J" first="Juliet E." last="Compston">Juliet E. Compston</name>
<name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name>
</country>
<country name="Nouvelle-Zélande"><noRegion><name sortKey="Dennison, Elaine M" sort="Dennison, Elaine M" uniqKey="Dennison E" first="Elaine M." last="Dennison">Elaine M. Dennison</name>
</noRegion>
</country>
<country name="États-Unis"><noRegion><name sortKey="Flahive, Julie" sort="Flahive, Julie" uniqKey="Flahive J" first="Julie" last="Flahive">Julie Flahive</name>
</noRegion>
<name sortKey="Anderson, Frederick A Jr" sort="Anderson, Frederick A Jr" uniqKey="Anderson F" first="Frederick A. Jr" last="Anderson">Frederick A. Jr Anderson</name>
<name sortKey="Gehlbach, Stephen H" sort="Gehlbach, Stephen H" uniqKey="Gehlbach S" first="Stephen H." last="Gehlbach">Stephen H. Gehlbach</name>
<name sortKey="Greenspan, Susan L" sort="Greenspan, Susan L" uniqKey="Greenspan S" first="Susan L." last="Greenspan">Susan L. Greenspan</name>
<name sortKey="Hooven, Frederick H" sort="Hooven, Frederick H" uniqKey="Hooven F" first="Frederick H." last="Hooven">Frederick H. Hooven</name>
<name sortKey="Lacroix, Andrea Z" sort="Lacroix, Andrea Z" uniqKey="Lacroix A" first="Andrea Z." last="Lacroix">Andrea Z. Lacroix</name>
<name sortKey="Lindsay, Robert" sort="Lindsay, Robert" uniqKey="Lindsay R" first="Robert" last="Lindsay">Robert Lindsay</name>
<name sortKey="Saag, Kenneth G" sort="Saag, Kenneth G" uniqKey="Saag K" first="Kenneth G." last="Saag">Kenneth G. Saag</name>
<name sortKey="Silverman, Stuart" sort="Silverman, Stuart" uniqKey="Silverman S" first="Stuart" last="Silverman">Stuart Silverman</name>
<name sortKey="Siris, Ethel S" sort="Siris, Ethel S" uniqKey="Siris E" first="Ethel S." last="Siris">Ethel S. Siris</name>
<name sortKey="Watts, Nelson B" sort="Watts, Nelson B" uniqKey="Watts N" first="Nelson B." last="Watts">Nelson B. Watts</name>
</country>
<country name="Canada"><region name="Ontario"><name sortKey="Adachi, Jonathan D" sort="Adachi, Jonathan D" uniqKey="Adachi J" first="Jonathan D." last="Adachi">Jonathan D. Adachi</name>
</region>
</country>
<country name="Belgique"><noRegion><name sortKey="Boonen, Steven" sort="Boonen, Steven" uniqKey="Boonen S" first="Steven" last="Boonen">Steven Boonen</name>
</noRegion>
</country>
<country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Chapurlat, Roland" sort="Chapurlat, Roland" uniqKey="Chapurlat R" first="Roland" last="Chapurlat">Roland Chapurlat</name>
</region>
<name sortKey="Roux, Christian" sort="Roux, Christian" uniqKey="Roux C" first="Christian" last="Roux">Christian Roux</name>
</country>
<country name="Espagne"><region name="Catalogne"><name sortKey="Diez Perez, Adolfo" sort="Diez Perez, Adolfo" uniqKey="Diez Perez A" first="Adolfo" last="Diez-Perez">Adolfo Diez-Perez</name>
</region>
</country>
<country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Coen Netelenbos, J" sort="Coen Netelenbos, J" uniqKey="Coen Netelenbos J" first="J." last="Coen Netelenbos">J. Coen Netelenbos</name>
</region>
</country>
<country name="Allemagne"><noRegion><name sortKey="Pfeilschifter, Johannes" sort="Pfeilschifter, Johannes" uniqKey="Pfeilschifter J" first="Johannes" last="Pfeilschifter">Johannes Pfeilschifter</name>
</noRegion>
</country>
<country name="Italie"><noRegion><name sortKey="Rossini, Maurizio" sort="Rossini, Maurizio" uniqKey="Rossini M" first="Maurizio" last="Rossini">Maurizio Rossini</name>
</noRegion>
</country>
<country name="Australie"><noRegion><name sortKey="Sambrook, Philip" sort="Sambrook, Philip" uniqKey="Sambrook P" first="Philip" last="Sambrook">Philip Sambrook</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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La maladie de Parkinson au Canada (serveur d'exploration)

Effect of co-morbidities on fracture risk: Findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW)

Effect of co-morbidities on fracture risk: Findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW)

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	La maladie de Parkinson au Canada (serveur d'exploration)
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